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Yesterday — 17 December 2024Main stream

“Unprecedented” decline in teen drug use continues, surprising experts

By: Beth Mole
17 December 2024 at 22:15

Teen drug use continued to fall in 2024, extending a dramatic decline spurred by the COVID-19 pandemic that experts expected would reverse now that the acute phase of the global crisis is well over.

But, according to data released Tuesday, the number of eighth, 10th, and 12th graders who collectively abstained from the use of alcohol, marijuana, or nicotine hit a new high this year. Use of illicit drugs also fell on the whole and use of non-heroin narcotics (Vicodin, OxyContin, Percocet) hit an all-time low.

"Many experts in the field had anticipated that drug use would resurge as the pandemic receded and social distancing restrictions were lifted," Richard Miech, team lead of the Monitoring the Future survey at the University of Michigan, said in a statement. "As it turns out, the declines have not only lasted but have dropped further."

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Huge math error corrected in black plastic study; authors say it doesn’t matter

By: Beth Mole
16 December 2024 at 22:23

Editors of the environmental chemistry journal Chemosphere have posted an eye-catching correction to a study reporting toxic flame retardants from electronics wind up in some household products made of black plastic, including kitchen utensils. The study sparked a flurry of media reports a few weeks ago that urgently implored people to ditch their kitchen spatulas and spoons. Wirecutter even offered a buying guide for what to replace them with.

The correction, posted Sunday, will likely take some heat off the beleaguered utensils. The authors made a math error that put the estimated risk from kitchen utensils off by an order of magnitude.

Specifically, the authors estimated that if a kitchen utensil contained middling levels of a key toxic flame retardant (BDE-209), the utensil would transfer 34,700 nanograms of the contaminant a day based on regular use while cooking and serving hot food. The authors then compared that estimate to a reference level of BDE-209 considered safe by the Environmental Protection Agency. The EPA's safe level is 7,000 ng—per kilogram of body weight—per day, and the authors used 60 kg as the adult weight (about 132 pounds) for their estimate. So, the safe EPA limit would be 7,000 multiplied by 60, yielding 420,000 ng per day. That's 12 times more than the estimated exposure of 34,700 ng per day.

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Before yesterdayMain stream

Bird flu jumps from birds to human in Louisiana; patient hospitalized

By: Beth Mole
13 December 2024 at 22:28

A person in Louisiana is hospitalized with H5N1 bird flu after having contact with sick and dying birds suspected of carrying the virus, state health officials announced Friday.

It is the first human H5N1 case detected in Louisiana. For now, the case is considered a "presumptive" positive until testing is confirmed by the Centers for Disease Control and Prevention. Health officials say that the risk to the public is low but caution people to stay away from any sick or dead birds. A spokesperson for Louisiana's health department told Ars that the hospitalized patient had contact with both backyard and wild birds.

Although the person has been hospitalized, their condition was not reported. The spokesperson said the department would not comment on the patient's condition due to patient confidentiality and an ongoing public health investigation.

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Americans spend more years being unhealthy than people in any other country

By: Beth Mole
13 December 2024 at 13:19

The gap of time between how long Americans live and how much of that time is spent in good health only grew wider in the last two decades, according to a new study published in JAMA Network Open.

The study, which looked at global health data between 2000 and 2019—prior to the COVID-19 pandemic—found the US stood out for its years of suffering. By 2019, Americans had a gap between their lifespan and their healthspan of 12.4 years, the largest gap of any of the 183 countries included in the study. The second largest gap was Australia's, at 12.1 years, followed by New Zealand at 11.8 years and the UK at 11.3 years.

America also stood out for having the largest burden of noncommunicable diseases in the world, as calculated by the years lived with disease or disability per 100,000 people.

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Americans spend more years being unhealthy than people in any other country

By: Beth Mole
13 December 2024 at 13:19

The gap of time between how long Americans live and how much of that time is spent in good health only grew wider in the last two decades, according to a new study published in JAMA Network Open.

The study, which looked at global health data between 2000 and 2019—prior to the COVID-19 pandemic—found the US stood out for its years of suffering. By 2019, Americans had a gap between their lifespan and their healthspan of 12.4 years, the largest gap of any of the 183 countries included in the study. The second largest gap was Australia's, at 12.1 years, followed by New Zealand at 11.8 years and the UK at 11.3 years.

America also stood out for having the largest burden of noncommunicable diseases in the world, as calculated by the years lived with disease or disability per 100,000 people.

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© Getty | Blend Images - JGI/Tom Grill

Prenatal test accidentally picks up cancer in 50% of those with wonky results

By: Beth Mole
5 December 2024 at 12:18

In 2013, researchers reported an eye-opening case of a healthy pregnant woman with a puzzling prenatal test result. A routine genetic screen using cell-free DNA—a highly accurate blood test—suggested her fetus had an extra copy of chromosome 13 (Patau syndrome) and only one copy of chromosome 18. These results are devastating; both conditions can cause severe abnormalities. Those with Patau syndrome often only survive a few days or weeks after birth. But, when doctors looked at scans and did additional pregnancy testing, all they found was a healthy fetus developing normally. The woman carried on with her uncomplicated pregnancy and gave birth to a healthy baby.

The alarming genetic results may have been written off as a freak testing flub. But soon after giving birth, the otherwise healthy 37-year-old mother of two reported severe pelvic pain. Imaging revealed what looked like multiple bone tumors, and she was subsequently diagnosed with metastatic small cell carcinoma of vaginal origin. Tragically, she has since died.

Testing of one of her tumors found that the cancerous cells had an increased number of chromosome 13 relative to chromosome 18. Her prenatal test had picked up her deadly cancer.

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Splash pads really are fountains of fecal material; CDC reports 10K illnesses

By: Beth Mole
3 December 2024 at 22:09

There's nothing quite like a deep dive into the shallow, vomitous puddles of children's splash pads. Even toeing the edge is enough to have one longing for the unsettling warmth of a kiddie pool. But the brave souls at the Centers for Disease Control and Prevention have done it, wading into 25 years' worth of records on gastrointestinal outbreaks linked to the wellsprings of fecal pathogens. And they unsurprisingly found enough retch-inducing results to make any modern-day John Snows want to start removing some water handles.

Between 1997 and 2022, splash pads across the country were linked to at least 60 outbreaks, with the largest sickening over 2,000 water frolickers in one go. In all, the outbreaks led to at least 10,611 illnesses, 152 hospitalizations, and 99 emergency department visits. People, mostly children, were sickened with pathogens including Cryptosporidium, Camplyobacter jejuni, Giardia duodenalis, Salmonella, Shigella, and norovirus, according to the analysis, published Tuesday in the CDC's Morbidity and Mortality Weekly Report. The tallies of outbreaks and illnesses are likely undercounts, given reporting delays and missed connections.

Though previous outbreak-based studies have provided bursts of data, the new analysis is the first to provide a comprehensive catalog of all the documented outbreaks since splash pads erupted in the 1990s. Together, they provide a clear, stomach-churning explanation of how the outbreaks keep happening. Basically, small children go into the watery playgrounds while they're sick and spread their germs.

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Raw milk producer optimistic after being shut down for bird flu detection

By: Beth Mole
3 December 2024 at 12:15

Bird flu has landed on a California farm that shuns virus-killing pasteurization, leading to a second recall of raw milk and a suspension of operations at the company, Raw Farm in Fresno County.

According to a November 27 alert by the California health department, officials in Santa Clara County found evidence of bird flu virus in retail samples of a batch of Raw Farm's milk, which has been recalled. It is the second time that retail testing has turned up positive results for the company and spurred a recall. The first contaminated batch was reported on November 24. The two recalled batches are those with lot codes 20241109 ("Best By" date of November 27, 2024) and 20241119 (Best By date of December 7, 2024).

In an email to Ars on Monday, Raw Farm CEO Mark McAfee said that none of the company's cows are visibly sick but that it appears that asymptomatic cows are shedding the avian influenza virus.

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Man suffers chemical burn that lasted months after squeezing limes

By: Beth Mole
27 November 2024 at 22:00

If Margaritaville were a real place, it should definitely keep a few dermatologists on hand.

In a case of an oft-overlooked food preparation risk, a 40-year-old man showed up to an allergy clinic in Texas with a severe burning rash on both his hands that had developed two days earlier. A couple of days later, it blistered. And a few weeks after that, the skin darkened and scaled. After several months, the skin on his hands finally returned to normal.

The culprit: lime juice and sunlight.

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Things aren’t looking good for infamous CEO of “health care terrorists”

By: Beth Mole
26 November 2024 at 16:33

Federal agents briefly detained infamous ex-hospital CEO Ralph de la Torre early last week and seized his phone, according to an investigative report from the Boston Globe.

De la Torre is the ultra-wealthy former CEO of the now-bankrupt hospital chain Steward, once the largest for-profit health care company in the country. Steward and de la Torre have been accused of being "health care terrorists" and practicing "third-world medicine" that killed and maimed patients as executives extracted millions in payouts, stripping the company of assets.

In September, de la Torre was held in criminal contempt of Congress for failing to abide by a congressional subpoena to attend a Senate hearing over the alleged corruption.

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Raw milk recalled for containing bird flu virus, California reports

By: Beth Mole
25 November 2024 at 18:25

Bird flu virus has been found in a batch of raw—unpasteurized—milk sold in California, prompting a recall issued at the state's request, health officials announced over the weekend.

No illnesses have yet been linked to the contaminated milk, made by Raw Farm, LLC of Fresno County. The contamination was found in testing by health officials in nearby Santa Clara County, who detected the virus in milk from a retail store. The state laboratory has confirmed the finding.

In a YouTube message from Raw Farm, a company representative called the contamination "not a big deal" and emphasized that the recall is only being done out of an abundance of caution.

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Surgeons remove 2.5-inch hairball from teen with rare Rapunzel syndrome

By: Beth Mole
21 November 2024 at 22:02

After a month of unexplained bouts of stomach pain, an otherwise healthy 16-year-old girl arrived at the emergency department of Massachusetts General Hospital actively retching and in severe pain.

A CT scan showed nothing unusual in her innards, and her urine and blood tests were normal. The same was found two weeks prior, when she had arrived at a different hospital complaining of stomach pain. She was discharged home with instructions to take painkillers, a medication for peptic ulcers, and another to prevent nausea and vomiting. The painkiller didn't help, and she didn't take the other two medications.

Her pain worsened, and something was clearly wrong. When she arrived at Mass General, her stomach was tender, and her heart rate was elevated. When doctors tried to give her a combination of medications for common causes of abdominal pain, she immediately vomited them back up.

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Horrifying medical device malfunction: Abdominal implant erupts from leg

By: Beth Mole
21 November 2024 at 12:30

On May 7, 2011, Georgia resident Tonya Brand noticed a pain on the inside of her right thigh. As the pain grew worse in the 4- to 5-inch area of her leg, she headed to a hospital. There, doctors suspected she had a blood clot. But an ultrasound the next day failed to find one. Instead, it revealed a mysterious toothpick-sized object lodged in Brand's leg.

Over the next few weeks, the painful area became a bulge, and on June 17, Brand put pressure on it. Unexpectedly, the protrusion popped, and a 1.5-inch metal wire came poking out of her leg, piercing her skin.

The piece of metal was later determined to be part of a metal filter she had implanted in a vein in her abdomen more than two years earlier, in March 2009, according to a lawsuit Brand filed. The filter was initially placed in her inferior vena cava (IVC), the body's largest vein tasked with bringing deoxygenated blood from the lower body back up to the heart. The filter is intended to catch blood clots, preventing them from getting into the lungs, where they could cause a life-threatening pulmonary embolism. Brand got the IVC filter ahead of a spinal surgery she had in 2009, which could boost her risk of clots.

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Novo Nordisk sells hit weight-loss drug in China—at fraction of US price

By: Beth Mole
19 November 2024 at 17:10

Patients in China will be able to purchase the blockbuster weight-loss drug Wegovy for 1,400 yuan, or about $193, just a fraction of the US list price of $1,349, according to media reports.

The price in China is in line with pricing elsewhere outside of the US. As Sen. Bernie Sanders (I-Vt.) noted in a September Senate hearing, Wegovy, made by Novo Nordisk, is sold for $265 in Canada, $186 in Denmark, $137 in Germany, and just $92 in the United Kingdom. In the hearing, Sanders and other senators grilled Novo Nordisk CEO Lars Jørgensen on the "outrageously high prices" in the US of Wegovy and the company's other popular GLP-1 drug, Ozempic, used for diabetes.

"What we are dealing with today is not just an issue of economics, it is not just an issue of corporate greed. It is a profound moral issue," Sanders said in opening remarks about the prices of the highly effective drugs.

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Trust in scientists hasn’t recovered from COVID. Some humility could help.

By: Beth Mole
18 November 2024 at 21:52

Scientists could win back trust lost during the COVID-19 pandemic if they just showed a little intellectual humility, according to a study published Monday in Nature Human Behavior.

It's no secret that scientists—and the science generally—took a hit during the health crisis. Public confidence in scientists fell from 87 percent in April 2000 to a low of 73 percent in October 2023, according to survey data from the Pew Research Center. And the latest Pew data released last week suggests it will be an uphill battle to regain what was lost, with confidence in scientists only rebounding three percentage points, to 76 percent in a poll from October.

Building trust

The new study in Nature Human Behavior may guide the way forward, though. The study encompasses five smaller studies probing the perceptions of scientists' trustworthiness, which previous research has linked to willingness to follow research-based recommendations.

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Are standing desks good for you? The answer is getting clearer.

By: Beth Mole
14 November 2024 at 18:13

Without question, inactivity is bad for us. Prolonged sitting is consistently linked to higher risks of cardiovascular disease and death. The obvious response to this frightful fate is to not sit— move. Even a few moments of exercise can have benefits, studies suggest. But in our modern times, sitting is hard to avoid, especially at the office. This has led to a range of strategies to get ourselves up, including the rise of standing desks. If you have to be tethered to a desk, at least you can do it while on your feet, the thinking goes.

However, studies on whether standing desks are beneficial have been sparse and sometimes inconclusive. Further, prolonged standing can have its own risks, and data on work-related sitting has also been mixed. While the final verdict on standing desks is still unclear, two studies out this year offer some of the most nuanced evidence yet about the potential benefits and risks of working on your feet.

Take a seat

For years, studies have pointed to standing desks improving markers for cardiovascular and metabolic health, such as lipid levels, insulin resistance, and arterial flow-mediated dilation (the ability of arteries to widen in response to increased blood flow). But it's unclear how significant those improvements are to averting bad health outcomes, such as heart attacks. One 2018 analysis suggested the benefits might be minor.

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Teen in critical condition with Canada’s first human case of H5 bird flu

By: Beth Mole
13 November 2024 at 14:51

A British Columbia teen who contracted Canada's first known human case of H5 bird flu has deteriorated swiftly in recent days and is now in critical condition, health officials reported Tuesday.

The teen's case was announced Saturday by provincial health officials, who noted that the teen had no obvious exposure to animals that could explain an infection with the highly pathogenic avian influenza. The teen tested positive for H5 bird flu at BC's public health laboratory, and the result is currently being confirmed by the National Microbiology Laboratory in Winnipeg.

The teen's case reportedly began with conjunctivitis, echoing the H5N1 human case reports in the US. The case then progressed to fever and cough, and the teen was admitted to BC's Children's hospital late Friday. The teen's condition varied throughout the weekend but had taken a turn for the worse by Tuesday, according to BC provincial health officer Bonnie Henry.

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Research monkeys still having a ball days after busting out of lab, police say

By: Beth Mole
8 November 2024 at 22:51

If you need any inspiration for cutting loose and relaxing this weekend, look no further than a free-wheeling troop of monkeys that broke out of their South Carolina research facility Wednesday and, as of noon Friday, were still "playfully exploring" with their newfound freedom.

In an update Friday, the police department of Yemassee, SC said that the 43 young, female rhesus macaque monkeys are still staying around the perimeter of the Alpha Genesis Primate Research Facility. "The primates are exhibiting calm and playful behavior, which is a positive indication," the department noted.

The fun-loving furballs got free after a caretaker "failed to secure doors" at the facility.

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After decades, FDA finally moves to pull ineffective decongestant off shelves

By: Beth Mole
7 November 2024 at 23:27

In a long-sought move, the Food and Drug Administration on Thursday formally began the process of abandoning oral doses of a common over-the-counter decongestant, which the agency concluded last year is not effective at relieving stuffy noses.

Specifically, the FDA issued a proposed order to remove oral phenylephrine from the list of drugs that drugmakers can include in over-the-counter products—also known as the OTC monograph. Once removed, drug makers will no longer be able to include phenylephrine in products for the temporary relief of nasal congestion.

"It is the FDA’s role to ensure that drugs are safe and effective," Patrizia Cavazzoni, director of the FDA’s Center for Drug Evaluation and Research, said in a statement. "Based on our review of available data and consistent with the advice of the advisory committee, we are taking this next step in the process to propose removing oral phenylephrine because it is not effective as a nasal decongestant."

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