Recently, chemists at Binghamton University learned that many tattoo inks in the US contain different pigments than those listed, or unlisted additives. One might expect the European Union, with its stricter regulations, to have fewer issues on that score, but according to a new paper published in the journal Analyst, that's not the case, particularly for green and blue tattoo inks. Most had components that were not listed on the label, and some included banned ingredients.

"Our work cannot say anything about the safety of tattoos, but we think it's an important first step in addressing the question 'Are tattoos safe?'" said co-author John Swierk, a chemist at Binghamton University. "If we don't know what's in a bottle of tattoo ink, then we cannot figure out what might be causing an adverse event in the near and long term, whether that’s an allergic reaction or something more serious. As a team, we aren't anti-tattoo, we just believe that clients and artists have a right to know what's in the inks they are using."

As previously reported, typical tattoo ink contains one or more pigments (which give the ink its color) within a "carrier package" to help deliver the pigments into the skin. The pigments are the same as those used in paints and textiles. They can be either small bits of solids or discrete molecules, such as titanium dioxide or iron oxide (for white or rust-brown colors, respectively). As for the carrier packages, most ink manufacturers use grain or rubbing alcohol, sometimes with a bit of witch hazel added to the mix to help the skin heal after the tattooing process. There may also be other additives to adjust the viscosity and keep pigment particles suspended in the carrier package.

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Recently, chemists at Binghamton University learned that many tattoo inks in the US contain different pigments than those listed, or unlisted additives. One might expect the European Union, with its stricter regulations, to have fewer issues on that score, but according to a new paper published in the journal Analyst, that's not the case, particularly for green and blue tattoo inks. Most had components that were not listed on the label, and some included banned ingredients.

"Our work cannot say anything about the safety of tattoos, but we think it's an important first step in addressing the question 'Are tattoos safe?'" said co-author John Swierk, a chemist at Binghamton University. "If we don't know what's in a bottle of tattoo ink, then we cannot figure out what might be causing an adverse event in the near and long term, whether that’s an allergic reaction or something more serious. As a team, we aren't anti-tattoo, we just believe that clients and artists have a right to know what's in the inks they are using."

As previously reported, typical tattoo ink contains one or more pigments (which give the ink its color) within a "carrier package" to help deliver the pigments into the skin. The pigments are the same as those used in paints and textiles. They can be either small bits of solids or discrete molecules, such as titanium dioxide or iron oxide (for white or rust-brown colors, respectively). As for the carrier packages, most ink manufacturers use grain or rubbing alcohol, sometimes with a bit of witch hazel added to the mix to help the skin heal after the tattooing process. There may also be other additives to adjust the viscosity and keep pigment particles suspended in the carrier package.

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Enlarge / BARCELONA, SPAIN - 2021/10/02: Spanish tattoo artist Oscar Garcia works on a man, during the Expo. Fira de Barcelona hosts the XXIV edition of the Barcelona Tattoo Expo where tattoo artists from Spain and other countries exhibit tattoos and tattoo material such as ink, needles and special machinery for tattoo work. (Photo by Ramon Costa/SOPA Images/LightRocket via Getty Images)

The Food and Drug Administration has been warning for years that some tattoo inks are brimming with bacteria—a large assortment that, when injected into your skin, can cause inflammatory reactions, allergic hypersensitivity, toxic responses, and, of course, straight-up infections. And, worse yet, the labels that say the inks are sterile are not reliable.

But, a recent recall of three tattoo pigments from the same manufacturer does a good job of illustrating the FDA's concerns. The water-based inks, all from Sierra Stain, had a bizarre array of bacteria, which were found at high levels, according to FDA testing.

One ink product—described as "Carolina Blue"—offered a microbial menagerie, with six odd species identified. They included a bacterium that often dwells in the gastrointestinal system and can inflame the mucosal lining of the intestines (Citrobacter braakii), a water-borne bacterium (Cupriavidus pauculus), and several that cause opportunistic infections (Citrobacter farmer, Achromobacter xylosoxidans, Ochrobactrum anthropi, and Pseudomonas fluorescens). These are bacteria that don't typically go about attacking humans but will if the conditions are right, including when they find themselves inside a human with a compromised immune system.

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