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Bird flu hit a dead end in Missouri, but it’s running rampant in California

As H5N1 bird flu continues to spread wildly among California dairy herds and farmworkers, federal health officials on Thursday offered some relatively good news about Missouri: The wily avian influenza virus does not appear to have spread from the state's sole human case, which otherwise remains a mystery.

On September 6, the Missouri Health department announced that a person with underlying health conditions tested positive for bird flu, and later testing indicated that it was an H5N1 strain related to the one currently circulating among US dairy cows. But, state and federal health officials were—and still are—stumped as to how that person became infected. The person had no known contact with infected animals and no contact with any obviously suspect animal products. No dairy herds in Missouri have tested positive, and no poultry farms had reported recent outbreaks, either. To date, all other human cases of H5N1 have been among farmworkers who had contact with H5N1-infected animals.

But aside from the puzzle, attention turned to the possibility that the unexplained Missouri case had passed on the infection to those around them. A household contact had symptoms at the same time as the person—aka the index case—and at least six health care workers developed illnesses after interacting with the person. One of the six had tested negative for bird flu around the time of their illness, but questions remained about the other five.

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© Getty | Matthew Ludak

Hummingbirds thrive on an extreme lifestyle. Here’s how.

Golden-Tailed Sapphire Hummingbird about to extract nectar from a yellow and red flower

Enlarge / Hummingbirds—like this golden-tailed sapphire from South America—draw the eye with their bright colors and busy, hovering flight. Biologists are drawn to understand the suite of adaptations they have evolved to survive extreme lifestyles. (credit: webguzs via Getty)

Everyone loves to watch hummingbirds—tiny, brightly colored blurs that dart about, hovering at flowers and pugnaciously defending their ownership of a feeder.

But to the scientists who study them, hummingbirds offer much more than an entertaining spectacle. Their small size and blazing metabolism mean they live life on a knife-edge, sometimes needing to shut down their bodies almost completely just to conserve enough energy to survive the night—or to migrate thousands of miles, at times across open ocean.

Their nectar-rich diet leads to blood-sugar levels that would put a person in a coma. And their zipping, zooming flight sometimes generates g-forces high enough to make a fighter pilot black out. The more researchers look, the more surprises lurk within those tiny bodies, the smallest in the avian world.

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Human bird flu cases tick up; second Colorado poultry farm reports spread

Human bird flu cases tick up; second Colorado poultry farm reports spread

Enlarge (credit: Getty | David Paul Morris)

A second Colorado poultry farm has reported a case of bird flu in a worker, marking the state's seventh human case this month amid the ongoing outbreak among dairy cows.

Colorado health officials said the seventh case is, for now, a presumptive positive. That means that the person has tested positive at the state level while confirmatory testing is being carried out at the Centers for Disease Control and Prevention.

The presumptive positive worker was at a poultry facility in the state's northeastern Weld County. In recent weeks, six workers at another poultry farm in Weld also tested positive for bird flu. In that facility, a commercial egg layer operation with about 1.8 million birds, workers were infected as they culled chickens known to be infected with the highly pathogenic avian influenza. Genetic testing of the virus in the birds and the workers indicated that they were infected with a strain of H5N1 closely related to the virus found spreading in dairy cattle and to dairy farm workers.

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Third human case of bird flu from cows—this one with respiratory symptoms

Holstein cows at a dairy farm.

Enlarge / Holstein cows at a dairy farm. (credit: Getty | John Carl D'Annibale)

Another dairy farm worker in Michigan has been infected with avian influenza virus, state and federal health officials reported Thursday.

The case marks the third time the outbreak of bird flu in milking cows is known to have spilled over to a human. The dairy farm worker in Michigan, like the others, had close contact with H5N1-infected dairy cows, suggesting another case of cow-to-human transmission.

But the case reported today is notable for being the first one involving respiratory symptoms. In the first two cases, the dairy workers (one in Texas, the other in Michigan) reported only eye infections (conjunctivitis). This third case—also in Michigan but from a different farm—reported upper respiratory symptoms, including cough, congestion, and sore throat, as well as eye discomfort and watery discharge, but not conjunctivitis. The worker was given an antiviral (Tamiflu) and is said to be recovering. No other workers on the farm have shown symptoms, and the worker's household contacts are being monitored.

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